Tetrahydrofuran

Tetrahydrofuran

THF

Molecular Formula: C4H8O

Colorless Transparent Liquid

Is widely used in organic synthesis, polymer industry and as organic solvents.

Product Description

Tetrahydrofuran (THF) is an organic compound with the molecular formula C4H8O. It is a colorless and transparent liquid with ether characteristics and is widely used in organic synthesis, polymer industry and as organic solvents.

Tetrahydrofuran appears as a colorless, transparent liquid, making it an ideal solvent in laboratories and industrial production. Its density is approximately 0.889 g/cm³, its boiling point is approximately 66°C, and its melting point is approximately -108°C. These physical properties make THF liquid at normal temperature and pressure, making it easy to operate and use. In addition, tetrahydrofuran has good solubility in many organic and inorganic substances, especially its strong solubility for organic compounds, which makes it one of the ideal solvents widely used in the field of organic synthesis.

From the perspective of chemical properties, the molecular formula of tetrahydrofuran is C4H8O, and its chemical structure contains a furan ring, which gives THF some unique chemical properties. First, THF can react under the action of a strong reducing agent and reduce to 1,4-butanediol. This reducing property makes THF play an important role in some specific synthetic reactions. Secondly, tetrahydrofuran may spontaneously polymerize in sunlight or air to form polymers. This characteristic requires attention to avoid light and ventilation during storage and use to prevent the generation of peroxides. In addition, THF has good stability, but under some special conditions, such as high temperature and pressure or the presence of catalysts, some chemical changes may occur.

Tetrahydrofuran plays an important role in the field of organic synthesis. Due to its good solvent properties and compatibility with many organic compounds, THF is often used as a solvent in reaction systems. In the preparation of metal-organic compounds, tetrahydrofuran is often used as a carrier for reducing agents such as metallic lithium. Its cyclic structure and molecular configuration make THF selective in some special reactions, helping to introduce specific functional groups in organic synthesis.

Specification

About Us
Zhejiang Amerisource New Material Co., Ltd.
Zhejiang Amerisource New Material Co., Ltd. is located at 26 Jianmin North Road, Sino-Italy Industrial Eco Park, Yuyao City, Zhejiang Province. lt is a professional China Tetrahydrofuran manufacturers and Tetrahydrofuran suppliers, specializing in the production of Tetrahydrofuran, occupying an area of approximately 80,000 square meters. The Meiyuan PBT project was officially put into operation at the end of 2019, focusing on the production of PBT and THF.
With a total investment of about 1.5 billion yuan, the PBT project has promoted the development of the resin synthesis industry in Zhejiang Province and enhanced the regional market competitiveness. The company is guided by social, economic, and human sustainable development principles. lt fully leverages its strengths and team spirit, establishes a sound modern enterprise management system, recruits and introduces highly educated and highly skilled talents, effectively develops and utilizes social resources, implements a strategy of technological innovation-driven development, and persistently follows the path of independent innovation to continuously enhance its core competitiveness.
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Chemical properties and structure of Tetrahydrofuran

Tetrahydrofuran, referred to as THF, is an oxygen-containing cyclic ether organic solvent with a molecular formula of C4H8O. THF's unique structure and chemical properties allow it to play a key role in many industrial fields.
Molecular Structure:
Tetrahydrofuran's molecular structure is the basis for its unique properties. It consists of four carbon atoms and one oxygen atom, taking the shape of a five-membered ring. This ring structure makes the THF molecule relatively small and polar, which plays a key role in its chemical reactions and dissolution properties. The simplicity and symmetry of this molecular structure provide THF with flexibility in many applications.
Polarity and solubility:
Since the THF molecule contains oxygen atoms, it exhibits a certain polarity. This enables THF to interact effectively with many organic and inorganic compounds. THF is an excellent solvent that can dissolve many organic substances, including fats, resins, polymers, etc. This solubility makes THF an indispensable solvent in synthetic chemistry, organic reactions, and the polymer industry.
Unsaturated properties:
The carbon-oxygen bond in the Tetrahydrofuran molecule has certain unsaturated properties, which provides the possibility for its participation in some chemical reactions. This unsaturated nature allows THF to exhibit higher reactivity in some specific reactions. For example, in synthesis reactions in the presence of catalysts, THF can serve as a reactant or medium and participate in the formation of ethers.
Stability and reactivity:
THF is relatively stable, but under some conditions, such as high temperature or high-energy ultraviolet radiation, it can polymerize. This reactivity causes THF to undergo unpredictable changes during some synthesis processes, and its stability needs to be paid attention to in practical applications. In the preparation of certain polymers, this reactivity becomes an advantageous property.
Properties of coordination with metals:
Tetrahydrofuran can form coordination compounds with many metals, and the complexes have different properties. This metal coordination property makes THF play a unique role in catalytic reactions and metal-organic chemistry. Its reactive properties with metals such as lithium and sodium provide some application potential in areas such as lithium-ion batteries.
Safety and environmental impact:
Although THF has important applications in chemical reactions and synthesis, it needs to be treated with caution due to its flammability and volatility. In addition, the waste treatment and discharge of THF also need to comply with environmental regulations to reduce potential impacts on the environment. In practical applications, appropriate safety measures must be taken to ensure the safety of personnel and the environment.

Industrial Application Areas of Tetrahydrofuran (THF)

Tetrahydrofuran, referred to as THF, is a multi-purpose organic solvent that plays an extensive and important role in the industrial field.
Pharmaceutical industry:
Tetrahydrofuran is an indispensable solvent in the pharmaceutical field. Its superior solubility properties make it ideal for drug synthesis. In the synthesis and extraction process of drugs, THF is often used to dissolve reactants and promote reactions between various organic compounds. In addition, THF is often used as an intermediate in the preparation of drugs, providing a basis for efficient and controllable drug production.
Chemical industry:
In the chemical industry, Tetrahydrofuran is an indispensable raw material in the production of many chemicals. One of its main uses is in the polymer industry, specifically in the preparation of polytetrafluoroethylene (PTFE). In polymerization reactions, THF plays a key role as the reaction medium to ensure high-quality polymer products. It is also involved in the production of other polymers such as polyurethane, polypropylene, etc., providing necessary materials for the plastics and rubber industries.
Solvents and Coatings Industry:
Tetrahydrofuran also has a prominent presence in the solvent and coatings industries. Due to its excellent solubility, THF is often used as a solvent for coatings and adhesives. It effectively dissolves a variety of resins and polymers, ensuring the coating has ideal flow and adhesion when applied. In addition, THF is also used to prepare some high-performance coating materials to improve the durability and corrosion resistance of the coating.
Electronic material preparation:
In the preparation of electronic materials, Tetrahydrofuran also has its unique applications. It is often used as a solvent for lithium-ion battery electrolytes, forming an electrolyte solution with lithium salts to provide good ionic conductivity. This is particularly critical in modern battery technology, enabling efficient energy storage in electronic devices.